Challenges in metal detection in pharmaceutical production

Any process employing machines having mechanical moving parts are bound to produce metal contamination that directly blendes in to the product / raw material. The real challenge is `detection' of this metal contamination - which is practically available with no definite shape / size / dimension / orientation.

The process machines viz. blenders, sifters, RMG, Roll Compacters, Multi Mills and finally also the Tablet Compression and Capsule filling machines have mechanical moving parts either SS316 / Hard Chrome plated / Phosphorous Bronze / Aluminum - that are directly in contact with the product at one or more stages. Metal Detectors can be installed even during the early stages of the process and are available in various versions to be fitted on to your raw material silos - for powder flowing with gravity or on vacuum conveyed powders.
The best location to find these contaminants is immediately after the Tablet Compression / Capsule Filling machines. The Tablet Compression machines allow the tablets to naturally flow in a single row - back-to-back, thus optimizing the sensitivity of the metal detectors. The tablet available in a row not only reduces the Product Effect, but also reduces the number of tablets getting rejected per reject cycle. The Metal detector if employed after the de-dusting system allows the tablets to pass in random bunches and affects the sensitivity ultimately. One cannot practically set the optimum operating sensitivity on such machines and will work with varying effects and would remain unstable - possibly also producing false signals. Also the number of tablets getting rejected is reduced drastically.

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